What are the long-term effects of crack cocaine?

In addition to the usual risks associated with cocaine use, crack users may experience severe respiratory problems, including coughing, shortness of breath, lung damage and bleeding.

Long-term effects from use of crack cocaine include severe damage to the heart, liver and kidneys. Users are more likely to have infectious diseases.

Continued daily use causes sleep deprivation and loss of appetite, resulting in malnutrition. Smoking crack cocaine also can cause aggressive and paranoid behavior.

As crack cocaine interferes with the way the brain processes chemicals, one needs more and more of the drug just to feel “normal.” Those who become addicted to crack cocaine (as with most other drugs) lose interest in other areas of life.

http://www.drugfreeworld.org/drugfacts/crackcocaine/effects-of-crack-cocaine.html